GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| BLCA | cis | rs9815354 | 1 | rs6599170 | chr3:41772718 | ULK4 | chr3:41288091-42003660:- | 0.63 | 9.74 | 3.64E-20 | Diastolic blood pressure |
| BLCA | cis | rs9815354 | 1 | rs6599175 | chr3:41786009 | ULK4 | chr3:41288091-42003660:- | -0.6 | -9.51 | 2.14E-19 | Diastolic blood pressure |
| BLCA | cis | rs9815354 | 1 | rs6599176 | chr3:41788492 | ULK4 | chr3:41288091-42003660:- | -0.62 | -9.75 | 3.3E-20 | Diastolic blood pressure |
| BLCA | cis | rs9815354 | 1 | rs6599178 | chr3:41842129 | ULK4 | chr3:41288091-42003660:- | 0.64 | 9.96 | 6.41E-21 | Diastolic blood pressure |
| BLCA | cis | rs9815354 | 1 | rs6599179 | chr3:41855284 | ULK4 | chr3:41288091-42003660:- | 0.64 | 10 | 4.42E-21 | Diastolic blood pressure |
| BLCA | cis | rs11723261 | 1 | rs6599318 | chr4:243968 | ZNF718 | chr4:53272-156488:+ | 0.34 | 4.55 | 7.25E-6 | Immune response to smallpox vaccine (IL-6) |
| BLCA | cis | rs2275426 | 1 | rs6656992 | chr1:46333068 | CCDC163P | chr1:45960581-45965646:- | -0.37 | -7 | 1.18E-11 | Body mass index |
| BLCA | cis | rs2275426 | 1 | rs6661910 | chr1:46290632 | CCDC163P | chr1:45960581-45965646:- | -0.37 | -7 | 1.18E-11 | Body mass index |
| BLCA | cis | rs2275426 | 1 | rs6662641 | chr1:46571509 | CCDC163P | chr1:45960581-45965646:- | -0.33 | -6.21 | 1.42E-9 | Body mass index |
| BLCA | cis | rs4660306 | 1 | rs6667191 | chr1:45982844 | CCDC163P | chr1:45960581-45965646:- | -0.81 | -16.62 | 4.15E-47 | Homocysteine levels |
| BLCA | cis | rs2275426 | 1 | rs6668284 | chr1:46354510 | CCDC163P | chr1:45960581-45965646:- | -0.37 | -7.03 | 9.62E-12 | Body mass index |
| BLCA | cis | rs2275426 | 1 | rs6669522 | chr1:46397941 | CCDC163P | chr1:45960581-45965646:- | -0.35 | -6.56 | 1.75E-10 | Body mass index |
| BLCA | cis | rs2275426 | 1 | rs6672898 | chr1:46290588 | CCDC163P | chr1:45960581-45965646:- | -0.37 | -7 | 1.18E-11 | Body mass index |
| BLCA | cis | rs2275426 | 1 | rs6675726 | chr1:46560643 | CCDC163P | chr1:45960581-45965646:- | -0.34 | -6.31 | 7.8E-10 | Body mass index |
| BLCA | cis | rs2275426 | 1 | rs6675726 | chr1:46560643 | MUTYH | chr1:45794915-45806142:- | 0.2 | 3.89 | 0.000117 | Body mass index |